Tuesday, December 11, 2007

Sexual Attraction Turns Genes Off...in female fish

"When a female is attracted to a male, entire suites of genes in her brain turn on and off, show biologists from The University of Texas at Austin studying swordtail fish.
“What we have not appreciated until now is how dynamic the genome is,” said Hofmann. “It is constantly changing and even in a very short period of time, 10 percent of the protein-coding genome can change its activity. We now have a genomic view of these dynamic processes within a social context.” The biologists next seek to identify specific regions in the brain where the genes are expressed. They also aim to enhance or inhibit specific genes and observe the resulting behavioral change. “We’d like to take a female who is a ‘high preference gal’ and make her a ‘low preference gal’ and vice versa,” said Cummings."

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