Tuesday, November 20, 2007

Possibly pluripotent stem cells from the skin! with a catch...

"It's a bit like learning how to turn lead into gold," said Dr. Lanza of the biotech company Advanced Cell Technology.

Scientists from Kyoto University "have created the equivalent of embryonic stem cells from ordinary skin cells, a breakthrough that could someday produce new treatments for disease without the explosive moral questions of embyro cloning."

"Two scientific teams chose different cell types from a tissue supplier. Yamanaka reprogrammed skin cells from the face of an unidentified 36-year-old woman, and Thomson's team worked with foreskin cells from a newborn. Thomson's team, which was working its way from embryonic to fetal to adult cells, is still analyzing its results with adult cells. Both labs did basically the same thing. Each used viruses to ferry four genes into the skin cells. These particular genes were known to turn other genes on and off, but just how they produced cells that mimic embryonic stem cells is a mystery."

Apparently there is a catch... "At this point, the technique disrupts the DNA of the skin cells, and that creates the potential for developing cancer. So it would be unacceptable for transplanting into a patient."

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1 Comments:

At November 30, 2007 at 7:29 PM , Blogger C. said...

Interesting thought: we have no "off switch" for pluripotent stem cells.

 

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